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1.

Modeling post-implantation stages of human development into early organogenesis with stem-cell-derived peri-gastruloids.

Liu, Lizhong; Oura, Seiya; Markham, Zachary; Hamilton, James N; Skory, Robin M; Li, Leijie; Sakurai, Masahiro; Wang, Lei; Pinzon-Arteaga, Carlos A; Plachta, Nicolas; Hon, Gary C; Wu, Jun.

Cell ; 186(18): 3776-3792.e16, 2023 08 31.

Article in English | MEDLINE | ID: mdl-37478861

2.

Structural and functional characterizations of infectivity and immune evasion of SARS-CoV-2 Omicron.

Cui, Zhen; Liu, Pan; Wang, Nan; Wang, Lei; Fan, Kaiyue; Zhu, Qianhui; Wang, Kang; Chen, Ruihong; Feng, Rui; Jia, Zijing; Yang, Minnan; Xu, Ge; Zhu, Boling; Fu, Wangjun; Chu, Tianming; Feng, Leilei; Wang, Yide; Pei, Xinran; Yang, Peng; Xie, Xiaoliang Sunney; Cao, Lei; Cao, Yunlong; Wang, Xiangxi.

Cell ; 185(5): 860-871.e13, 2022 03 03.

Article in English | MEDLINE | ID: mdl-35120603

3.

Virological characteristics of the SARS-CoV-2 Omicron BA.2 subvariants, including BA.4 and BA.5.

Kimura, Izumi; Yamasoba, Daichi; Tamura, Tomokazu; Nao, Naganori; Suzuki, Tateki; Oda, Yoshitaka; Mitoma, Shuya; Ito, Jumpei; Nasser, Hesham; Zahradnik, Jiri; Uriu, Keiya; Fujita, Shigeru; Kosugi, Yusuke; Wang, Lei; Tsuda, Masumi; Kishimoto, Mai; Ito, Hayato; Suzuki, Rigel; Shimizu, Ryo; Begum, Mst Monira; Yoshimatsu, Kumiko; Kimura, Kanako Terakado; Sasaki, Jiei; Sasaki-Tabata, Kaori; Yamamoto, Yuki; Nagamoto, Tetsuharu; Kanamune, Jun; Kobiyama, Kouji; Asakura, Hiroyuki; Nagashima, Mami; Sadamasu, Kenji; Yoshimura, Kazuhisa; Shirakawa, Kotaro; Takaori-Kondo, Akifumi; Kuramochi, Jin; Schreiber, Gideon; Ishii, Ken J; Hashiguchi, Takao; Ikeda, Terumasa; Saito, Akatsuki; Fukuhara, Takasuke; Tanaka, Shinya; Matsuno, Keita; Sato, Kei.

Cell ; 185(21): 3992-4007.e16, 2022 10 13.

Article in English | MEDLINE | ID: mdl-36198317

4.

Virological characteristics of the SARS-CoV-2 Omicron BA.2 spike.

Yamasoba, Daichi; Kimura, Izumi; Nasser, Hesham; Morioka, Yuhei; Nao, Naganori; Ito, Jumpei; Uriu, Keiya; Tsuda, Masumi; Zahradnik, Jiri; Shirakawa, Kotaro; Suzuki, Rigel; Kishimoto, Mai; Kosugi, Yusuke; Kobiyama, Kouji; Hara, Teppei; Toyoda, Mako; Tanaka, Yuri L; Butlertanaka, Erika P; Shimizu, Ryo; Ito, Hayato; Wang, Lei; Oda, Yoshitaka; Orba, Yasuko; Sasaki, Michihito; Nagata, Kayoko; Yoshimatsu, Kumiko; Asakura, Hiroyuki; Nagashima, Mami; Sadamasu, Kenji; Yoshimura, Kazuhisa; Kuramochi, Jin; Seki, Motoaki; Fujiki, Ryoji; Kaneda, Atsushi; Shimada, Tadanaga; Nakada, Taka-Aki; Sakao, Seiichiro; Suzuki, Takuji; Ueno, Takamasa; Takaori-Kondo, Akifumi; Ishii, Ken J; Schreiber, Gideon; Sawa, Hirofumi; Saito, Akatsuki; Irie, Takashi; Tanaka, Shinya; Matsuno, Keita; Fukuhara, Takasuke; Ikeda, Terumasa; Sato, Kei.

Cell ; 185(12): 2103-2115.e19, 2022 06 09.

Article in English | MEDLINE | ID: mdl-35568035

5.

Revisiting astrocyte to neuron conversion with lineage tracing in vivo.

Wang, Lei-Lei; Serrano, Carolina; Zhong, Xiaoling; Ma, Shuaipeng; Zou, Yuhua; Zhang, Chun-Li.

Cell ; 184(21): 5465-5481.e16, 2021 10 14.

Article in English | MEDLINE | ID: mdl-34582787

6.

Structural insights into the human D1 and D2 dopamine receptor signaling complexes.

Zhuang, Youwen; Xu, Peiyu; Mao, Chunyou; Wang, Lei; Krumm, Brian; Zhou, X Edward; Huang, Sijie; Liu, Heng; Cheng, Xi; Huang, Xi-Ping; Shen, Dan-Dan; Xu, Tinghai; Liu, Yong-Feng; Wang, Yue; Guo, Jia; Jiang, Yi; Jiang, Hualiang; Melcher, Karsten; Roth, Bryan L; Zhang, Yan; Zhang, Cheng; Xu, H Eric.

Cell ; 184(4): 931-942.e18, 2021 02 18.

Article in English | MEDLINE | ID: mdl-33571431

7.

Developing Covalent Protein Drugs via Proximity-Enabled Reactive Therapeutics.

Li, Qingke; Chen, Qu; Klauser, Paul C; Li, Mengyuan; Zheng, Feng; Wang, Nanxi; Li, Xiaoying; Zhang, Qianbing; Fu, Xuemei; Wang, Qian; Xu, Yang; Wang, Lei.

Cell ; 182(1): 85-97.e16, 2020 07 09.

Article in English | MEDLINE | ID: mdl-32579975

8.

Cryo-EM Structure of the Human Cannabinoid Receptor CB2-G_i Signaling Complex.

Xing, Changrui; Zhuang, Youwen; Xu, Ting-Hai; Feng, Zhiwei; Zhou, X Edward; Chen, Maozi; Wang, Lei; Meng, Xing; Xue, Ying; Wang, Junmei; Liu, Heng; McGuire, Terence Francis; Zhao, Gongpu; Melcher, Karsten; Zhang, Cheng; Xu, H Eric; Xie, Xiang-Qun.

Cell ; 180(4): 645-654.e13, 2020 02 20.

Article in English | MEDLINE | ID: mdl-32004460

9.

Single-cell profiling identifies mechanisms of inflammatory heterogeneity in chronic rhinosinusitis.

Wang, Weiqing; Xu, Yi; Wang, Lun; Zhu, Zhenzhen; Aodeng, Surita; Chen, Hui; Cai, Menghua; Huang, Zhihao; Han, Jinbo; Wang, Lei; Lin, Yuxi; Hu, Yu; Zhou, Liangrui; Wang, Xiaowei; Zha, Yang; Jiang, Weihong; Gao, Zhiqiang; He, Wei; Lv, Wei; Zhang, Jianmin.

Nat Immunol ; 23(10): 1484-1494, 2022 10.

Article in English | MEDLINE | ID: mdl-36138182

10.

Therapeutic Potential of PTBP1 Inhibition, If Any, Is Not Attributed to Glia-to-Neuron Conversion.

Wang, Lei-Lei; Zhang, Chun-Li.

Annu Rev Neurosci ; 46: 1-15, 2023 07 10.

Article in English | MEDLINE | ID: mdl-36750409

11.

Connecting blood and intratumoral T_reg cell activity in predicting future relapse in breast cancer.

Wang, Lei; Simons, Diana L; Lu, Xuyang; Tu, Travis Y; Solomon, Shawn; Wang, Roger; Rosario, Anthony; Avalos, Christian; Schmolze, Daniel; Yim, John; Waisman, James; Lee, Peter P.

Nat Immunol ; 20(9): 1220-1230, 2019 09.

Article in English | MEDLINE | ID: mdl-31285626

12.

Organ-level quorum sensing directs regeneration in hair stem cell populations.

Chen, Chih-Chiang; Wang, Lei; Plikus, Maksim V; Jiang, Ting Xin; Murray, Philip J; Ramos, Raul; Guerrero-Juarez, Christian F; Hughes, Michael W; Lee, Oscar K; Shi, Songtao; Widelitz, Randall B; Lander, Arthur D; Chuong, Cheng Ming.

Cell ; 161(2): 277-90, 2015 Apr 09.

Article in English | MEDLINE | ID: mdl-25860610

13.

Generation of gene-modified cynomolgus monkey via Cas9/RNA-mediated gene targeting in one-cell embryos.

Niu, Yuyu; Shen, Bin; Cui, Yiqiang; Chen, Yongchang; Wang, Jianying; Wang, Lei; Kang, Yu; Zhao, Xiaoyang; Si, Wei; Li, Wei; Xiang, Andy Peng; Zhou, Jiankui; Guo, Xuejiang; Bi, Ye; Si, Chenyang; Hu, Bian; Dong, Guoying; Wang, Hong; Zhou, Zuomin; Li, Tianqing; Tan, Tao; Pu, Xiuqiong; Wang, Fang; Ji, Shaohui; Zhou, Qi; Huang, Xingxu; Ji, Weizhi; Sha, Jiahao.

Cell ; 156(4): 836-43, 2014 Feb 13.

Article in English | MEDLINE | ID: mdl-24486104

14.

VHL suppresses autophagy and tumor growth through PHD1-dependent Beclin1 hydroxylation.

Wang, Zheng; Yan, Meisi; Ye, Leiguang; Zhou, Qimin; Duan, Yuran; Jiang, Hongfei; Wang, Lei; Ouyang, Yuan; Zhang, Huahe; Shen, Yuli; Ji, Guimei; Chen, Xiaohan; Tian, Qi; Xiao, Liwei; Wu, Qingang; Meng, Ying; Liu, Guijun; Ma, Leina; Lei, Bo; Lu, Zhimin; Xu, Daqian.

EMBO J ; 43(6): 931-955, 2024 Mar.

Article in English | MEDLINE | ID: mdl-38360997

15.

Genetically encoded chemical probes in cells reveal the binding path of urocortin-I to CRF class B GPCR.

Coin, Irene; Katritch, Vsevolod; Sun, Tingting; Xiang, Zheng; Siu, Fai Yiu; Beyermann, Michael; Stevens, Raymond C; Wang, Lei.

Cell ; 155(6): 1258-69, 2013 Dec 05.

Article in English | MEDLINE | ID: mdl-24290358

16.

Plant receptor-like protein activation by a microbial glycoside hydrolase.

Sun, Yue; Wang, Yan; Zhang, Xiaoxiao; Chen, Zhaodan; Xia, Yeqiang; Wang, Lei; Sun, Yujing; Zhang, Mingmei; Xiao, Yu; Han, Zhifu; Wang, Yuanchao; Chai, Jijie.

Nature ; 610(7931): 335-342, 2022 10.

Article in English | MEDLINE | ID: mdl-36131021

17.

Attenuated fusogenicity and pathogenicity of SARS-CoV-2 Omicron variant.

Suzuki, Rigel; Yamasoba, Daichi; Kimura, Izumi; Wang, Lei; Kishimoto, Mai; Ito, Jumpei; Morioka, Yuhei; Nao, Naganori; Nasser, Hesham; Uriu, Keiya; Kosugi, Yusuke; Tsuda, Masumi; Orba, Yasuko; Sasaki, Michihito; Shimizu, Ryo; Kawabata, Ryoko; Yoshimatsu, Kumiko; Asakura, Hiroyuki; Nagashima, Mami; Sadamasu, Kenji; Yoshimura, Kazuhisa; Sawa, Hirofumi; Ikeda, Terumasa; Irie, Takashi; Matsuno, Keita; Tanaka, Shinya; Fukuhara, Takasuke; Sato, Kei.

Nature ; 603(7902): 700-705, 2022 03.

Article in English | MEDLINE | ID: mdl-35104835

18.

Memory B cell repertoire from triple vaccinees against diverse SARS-CoV-2 variants.

Wang, Kang; Jia, Zijing; Bao, Linilin; Wang, Lei; Cao, Lei; Chi, Hang; Hu, Yaling; Li, Qianqian; Zhou, Yunjiao; Jiang, Yinan; Zhu, Qianhui; Deng, Yongqiang; Liu, Pan; Wang, Nan; Wang, Lin; Liu, Min; Li, Yurong; Zhu, Boling; Fan, Kaiyue; Fu, Wangjun; Yang, Peng; Pei, Xinran; Cui, Zhen; Qin, Lili; Ge, Pingju; Wu, Jiajing; Liu, Shuo; Chen, Yiding; Huang, Weijin; Wang, Qiao; Qin, Cheng-Feng; Wang, Youchun; Qin, Chuan; Wang, Xiangxi.

Nature ; 603(7903): 919-925, 2022 03.

Article in English | MEDLINE | ID: mdl-35090164

19.

Enhanced fusogenicity and pathogenicity of SARS-CoV-2 Delta P681R mutation.

Saito, Akatsuki; Irie, Takashi; Suzuki, Rigel; Maemura, Tadashi; Nasser, Hesham; Uriu, Keiya; Kosugi, Yusuke; Shirakawa, Kotaro; Sadamasu, Kenji; Kimura, Izumi; Ito, Jumpei; Wu, Jiaqi; Iwatsuki-Horimoto, Kiyoko; Ito, Mutsumi; Yamayoshi, Seiya; Loeber, Samantha; Tsuda, Masumi; Wang, Lei; Ozono, Seiya; Butlertanaka, Erika P; Tanaka, Yuri L; Shimizu, Ryo; Shimizu, Kenta; Yoshimatsu, Kumiko; Kawabata, Ryoko; Sakaguchi, Takemasa; Tokunaga, Kenzo; Yoshida, Isao; Asakura, Hiroyuki; Nagashima, Mami; Kazuma, Yasuhiro; Nomura, Ryosuke; Horisawa, Yoshihito; Yoshimura, Kazuhisa; Takaori-Kondo, Akifumi; Imai, Masaki; Tanaka, Shinya; Nakagawa, So; Ikeda, Terumasa; Fukuhara, Takasuke; Kawaoka, Yoshihiro; Sato, Kei.

Nature ; 602(7896): 300-306, 2022 02.

Article in English | MEDLINE | ID: mdl-34823256

20.

BA.2.12.1, BA.4 and BA.5 escape antibodies elicited by Omicron infection.

Cao, Yunlong; Yisimayi, Ayijiang; Jian, Fanchong; Song, Weiliang; Xiao, Tianhe; Wang, Lei; Du, Shuo; Wang, Jing; Li, Qianqian; Chen, Xiaosu; Yu, Yuanling; Wang, Peng; Zhang, Zhiying; Liu, Pulan; An, Ran; Hao, Xiaohua; Wang, Yao; Wang, Jing; Feng, Rui; Sun, Haiyan; Zhao, Lijuan; Zhang, Wen; Zhao, Dong; Zheng, Jiang; Yu, Lingling; Li, Can; Zhang, Na; Wang, Rui; Niu, Xiao; Yang, Sijie; Song, Xuetao; Chai, Yangyang; Hu, Ye; Shi, Yansong; Zheng, Linlin; Li, Zhiqiang; Gu, Qingqing; Shao, Fei; Huang, Weijin; Jin, Ronghua; Shen, Zhongyang; Wang, Youchun; Wang, Xiangxi; Xiao, Junyu; Xie, Xiaoliang Sunney.

Nature ; 608(7923): 593-602, 2022 08.

Article in English | MEDLINE | ID: mdl-35714668

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